| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4164402 | The Journal of Pediatrics | 2016 | 9 Pages |
Abstract
Cancer screening in BWS could be differentiated on the basis of (epi)genotype and target specific histotypes. Patients with ICR1-GoM and UPD should undergo renal ultrasonography scanning, given their risk of Wilms tumor. Alpha feto protein monitoring for heptaoblastoma is suggested in patients with UPD. Adrenal carcinoma may deserve screening in patients with UPD. Patients with CDKN1C mutations may deserve neuroblastoma screening based on urinary markers and ultrasonography scanning. Finally, screening appears questionable in cases of ICR2-LoM, given low tumor risk.
Keywords
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Authors
Alessandro MD, PhD, Cristina MD, Giuseppina MD, Evelise PhD, Silvia PhD, Lidia MD, PhD, Andrea MD, PhD, Giovanni Battista MD, PhD,