Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4164556 | The Journal of Pediatrics | 2016 | 7 Pages |
Abstract
This study reports rates of GFR decline, HTN, and proteinuria in a small but well-phenotyped ARPKD cohort. The relatively slow rate of GFR decline in subjects with ARPKD and absence of significant proteinuria suggest that these standard clinical measures may have limited utility in assessing therapeutic interventions and highlight the need for other ARPKD kidney disease progression biomarkers.
Keywords
EGFRUPCHTNARPKDGFRCKiDLVHiGFRObstructive uropathyChronic Kidney Disease in Childrenchronic kidney diseaseautosomal recessive polycystic kidney diseaseHypertensionACEI یا angiotensin convert enzyme inhibitorangiotensin-converting enzyme inhibitorestimated glomerular filtration rateCKDGlomerular filtration rateLeft ventricular hypertrophy
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Authors
Katherine M. MD, Matthew MS, Erum A. MD, Bradley A. MD, Susan L. MD, PhD,