Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4165429 | The Journal of Pediatrics | 2013 | 4 Pages |
Abstract
We investigated mechanisms of the false-positive test results on rapid-antigen detection test (RADT) for group A Streptococcal (GAS) pharyngitis. Most RADT false-positives (76%) were associated with polymerase chain reaction-positive GAS results, suggesting that RADT specificity could be considered close to 100%. Finding that 61% of GAS culture-negative but RADT-positive cases were positive on both GAS polymerase chain reaction and Staphylococcus aureus testing, we posit bacterial inhibition as causative.
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Authors
Jérémie F. MD, MSc, Robert MD, Philippe MD, PhD, Corinne MD, Patrice MD, Camille MD, Sandrine MD, François MD, Franck MD, Patricia MD, PhD, Martin MD, PhD, Edouard PharmD, PhD,