Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4166509 | The Journal of Pediatrics | 2010 | 9 Pages |
Abstract
The relatively large effect of these common variants near melanocortin 4 receptor on general and visceral adiposity in childhood, especially in girls, could prove helpful in elucidating the molecular mechanisms underlying the development of obesity in early life.
Keywords
Subcutaneous abdominal adipose tissueHTRDXAMC4RHWEAPEXMAFAfrican-AmericanHomeostasis model assessmentMRIvisceral adipose tissueMagnetic resonance imagingHardy-Weinberg equilibriumdual-energy X-ray absorptiometryPercent body fatFTObody mass indexBMILinkage disequilibriumconfidence intervalminor allele frequenciesVATGenome-wide association studyGWASInsulin resistanceHOMA%BFSingle nucleotide polymorphismSNPSAATmelanocortin 4 receptor
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Authors
Gaifen PhD, Haidong MD, PhD, Vasiliki PhD, Bernard PhD, Paule PhD, Frank A. PhD, Yanbin MD, PhD, Harold PhD,