Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4166522 | The Journal of Pediatrics | 2010 | 4 Pages |
Abstract
After a birth dose of acellular pertussis (aP) and diphtheria (DT)aP-hepatitis B virus (HBV)-inactivated polio vaccine (IPV)/Haemophilus influenza type b (Hib) at 2, 4, and 6 months, a booster dose of DTaP-HBV-IPV/Hib at 12 to 23 months induced strong anti-pertussis booster responses. Thus, neonatal aP priming did not lead to immune tolerance to pertussis antigens. However, it elicited bystander interference on HBV, Hib, and diphtheria responses.
Keywords
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Authors
Markus Knuf, Heinz-Josef Schmitt, Jeanne-Marie Jacquet, Alix Collard, Dorothee Kieninger, Claudius U. Meyer, Claire-Anne Siegrist, Fred Zepp,