Adverse Neurodevelopment in Preterm Infants with Postnatal Sepsis or Necrotizing Enterocolitis is Mediated by White Matter Abnormalities on Magnetic Resonance Imaging at Term

Article ID	Journal	Published Year	Pages	File Type
4167047	The Journal of Pediatrics	2008	7 Pages	PDF

Abstract

Preterm infants with sepsis/NEC are at greater risk of motor impairment at 2 years, which appears to be mediated by WMA. These findings may assist in defining a neuroprotective target in preterm infants with sepsis/NEC.

Keywords

NEC GMA CoNS MDI PDI PDA WMA Coagulase negative staphylococci MRI Necrotizing enterocolitis white matter abnormality Magnetic resonance image Psychomotor Developmental Index Mental Developmental Index Periventricular leukomalacia Cerebrospinal fluid CSF Patent ductus arteriosus PVL C-reactive protein CRP

Related Topics

Health Sciences Medicine and Dentistry Perinatology, Pediatrics and Child Health

Preview

Adverse Neurodevelopment in Preterm Infants with Postnatal Sepsis or Necrotizing Enterocolitis is Mediated by White Matter Abnormalities on Magnetic Resonance Imaging at Term

Authors

Divyen K. MB, ChB, Lex W. MD, Peter J. PhD, Merilyn RN, Andrew J. MD, Rod W. MB, ChB, PhD, Terrie E. MD,