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Intravenous Sildenafil in the Treatment of Neonates with Persistent Pulmonary Hypertension

Article ID Journal Published Year Pages File Type
4167287 The Journal of Pediatrics 2009 8 Pages PDF
Abstract
IV sildenafil was well tolerated, and acute and sustained improvements in oxygenation were noted in those neonates who received the higher infusion doses.
Keywords
iNOType 5 PhosphodiesterasePPHNFiO2PaO2PDE5cGMPECMOcAMPCyclic adenosine monophosphateInhaled nitric oxideextracorporeal membrane oxygenationIntravenousOxygenation indexpartial pressure of oxygen in arterial bloodcyclic guanosine monophosphatePersistent pulmonary hypertension of the newbornFraction of inspired oxygen
Related Topics
Health Sciences Medicine and Dentistry Perinatology, Pediatrics and Child Health
Preview
Intravenous Sildenafil in the Treatment of Neonates with Persistent Pulmonary Hypertension
Authors
Robin H. MD, John P. MD, Christine MD, Ghazwan MB, PhD, Maria MSc, Michael MSc, PhD, David L. MD,
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Journal
The Journal of Pediatrics
Journal: The Journal of Pediatrics
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iNO
Type 5 Phosphodiesterase
PPHN
FiO2
PaO2
PDE5
cGMP
ECMO
cAMP
Cyclic adenosine monophosphate
Inhaled nitric oxide
extracorporeal membrane oxygenation
Intravenous
Oxygenation index
partial pressure of oxygen in arterial blood
cyclic guanosine monophosphate
Persistent pulmonary hypertension of the newborn
Fraction of inspired oxygen
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