Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4167399 | The Journal of Pediatrics | 2009 | 7 Pages |
Abstract
Pulmonary abnormalities are common in infants and young children with CF and relate to neutrophilic inflammation and infection with P. aeruginosa. Current models of care for infants with CF fail to prevent respiratory sequelae. Bronchiectasis is a clinically relevant endpoint that could be used for intervention trials that commence soon after CF is diagnosed after NBS.
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Authors
Stephen M. MA, MB BChir, PhD, Siobhain BSc (hons), PhD, Conor MBBS, Dip Ch, FRANZCR, Tonia MBChB (hons), FRACP, Britta S. MD, DEAA, Luke W. BSc (hons), Catherine L. BSc (hons), PhD, Nicholas BSc, MSc, F Ed TC, PhD, Barry MD, PhD, Sarath MB ChB, MRCP,