| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4167626 | The Journal of Pediatrics | 2010 | 7 Pages |
Abstract
Long-term sequelae of type 1 diabetes include vasculopathies. Endothelial progenitor cells promote vascular health by facilitating endothelial integrity and function. Lower CD34+CD133+CD31+ cells may be a harbinger of future macrovascular disease risk. Higher circulating CD34+CD45- cells may reflect ongoing endothelial damage. These cells are potential biomarkers to guide therapeutic interventions to enhance endothelial function and to prevent progression to overt vascular disease.
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Authors
Linda A. MD, MPH, Aneesh MD, MS, Chandan PhD, Myka BS, Julie MS, Laura E. BS, Izlin MD, David A. MD, Laura S. MD,