Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4167998 | The Journal of Pediatrics | 2009 | 4 Pages |
Abstract
We evaluated Inter-alpha inhibitor proteins (IaIp) as a diagnostic marker in neonatal sepsis. Samples were collected from 573 neonates who were examined for suspected sepsis. IaIp level was significantly lower in the septic group (121 ± 71 mg/L) than in the non-septic group (322 ± 91 mg/L). The optimal cutoff value with the receiver operating characteristic curve was â¤177 mg/L (sensitivity, 89.5%; specificity, 99%; positive predictive value, 95%; negative predictive value, 98%) with area under the curve of 0.94. IaIp is a more reliable diagnostic marker for neonatal sepsis than other available tests.
Keywords
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Authors
Hala MD, Kultar MD, Juliza Huang, Ed Siryaporn, Yow-Pin MD, PhD, James F. MD,