Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4168207 | The Journal of Pediatrics | 2010 | 11 Pages |
Abstract
Children with DS exhibited distinct abnormalities in cells of the innate immune system. Most strikingly, they had a high number of proinflammatory CD14dimCD16+ monocytes. This elevated level of CD14dimCD16+ monocytes may play an important role in the onset and maintenance of chronic inflammatory disease in DS.
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Authors
Beatrijs L.P. MD, Grada M. PhD, Jan L.L. MD, PhD, Louis MD, PhD,