Article ID Journal Published Year Pages File Type
4168548 The Journal of Pediatrics 2008 5 Pages PDF
Abstract
Two siblings born to a mother with Wilson's disease, who was taking D-penicillamine, developed transient goitrous hypothyroidism. A prospective evaluation of 5 patients with Wilson's disease taking and not taking D-penicillamine for as long as 9.5 years showed subclinical hypothyroidism. D-penicillamine probably inhibited thyroperoxidase activity in utero in healthy infants and during childhood in patients with Wilson's disease.
Related Topics
Health Sciences Medicine and Dentistry Perinatology, Pediatrics and Child Health
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