| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4168646 | The Journal of Pediatrics | 2007 | 5 Pages |
ObjectiveTo investigate whether parental hypertension (HTN) affects children’s body mass index (BMI) and cardiovascular reactivity (CVR) over time.Study designA longitudinal study of 315 students (black: 23 females, 19 males; white: 142 females, 131 males) was conducted in the public schools of Obion County, Tennessee, between 1987 and 1992. BMI and BMI z scores were calculated. The CVR task was a series of video games (taking ∼10 minutes to play) given to the same students in their third-, fourth-, fifth-, seventh-, and eighth-grade years. CVR was defined as the change in blood pressure (Δ_BP) or heart rate (Δ_HR) between before playing and while playing the video game. Positive parental history of HTN (27.6%) was defined as at least 1 parent with HTN. Multivariable regression analyses were performed to estimate the effects of parental HTN on children’s BMI and CVR over time.ResultsChildren with parental HTN had significant higher BMI, BMI z score, and R_BP than did children without parental HTN (BMI: 21.6 vs 19.9, P = .001; BMI z score: 1.6 vs 1.1, P = .003; R_SBP: 112.6 vs 110.4 mm Hg, P = .01; R_DBP 62.7 vs 60.6 mm Hg, P = .003) after adjustment for covariates. Increased CVR was observed in children with parental HTN compared with children without parental HTN but was statistically significant only for SBP (Δ_SBP: 17.2 vs 14.9 mm Hg; P = .01) after adjustment for covariates.ConclusionsParental HTN independently predicted children’s BMI, BMI z score, resting BP, and BP reactivity.
