Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4169246 | The Journal of Pediatrics | 2006 | 10 Pages |
Abstract
A targeted array detects a substantial proportion of abnormalities even in those patients who have already had extensive cytogenetic and/or fluorescence in situ hybridization testing. This study, although not a controlled ascertainment of subjects with specific selection criteria, accurately reflects the reality of clinical cytogenetic practice and provides an estimate of the cytogenetic abnormalities that can be identified with a targeted microarray in a diagnostic laboratory. Microarray analysis likely doubles the current yield of abnormal results detected by conventional cytogenetic analysis.
Keywords
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Authors
Lisa G. PhD, Catherine D. BS, Reza PhD, Emily BS, Kyle MS, Blake C. PhD, Bassem A. MD,