| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4169438 | The Journal of Pediatrics | 2006 | 4 Pages |
Abstract
Two children presented with acute hepatitis after starting therapy with atomoxetine (Strattera®). In one child, no competing diagnosis could be identified, and liver injury resolved completely on withdrawal of the medication. In the second child, the evaluation was suggestive of type 1 autoimmune hepatitis; she subsequently improved with removal of atomoxetine and concomitant immunosuppressive therapy. Atomoxetine may cause clinically significant hepatotoxicity either by metabolic idiosyncrasy or by inducing autoimmune hepatitis.
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Authors
Joel R. Lim, Philip R. Faught, Naga P. Chalasani, Jean P. Molleston,