Article ID Journal Published Year Pages File Type
4171975 Paediatrics and Child Health 2016 5 Pages PDF
Abstract

Neuroblastoma is the most common extra cranial solid tumour in childhood. It is a fascinating and enigmatic tumour showing behaviour ranging from biological resistance to multimodal cancer therapies to complete spontaneous regression. The majority of children presenting with neuroblastoma have ‘high risk disease’ with distant metastases at primary diagnosis associated with considerable (more than50%) mortality. New targeted therapies are crucial to improve survival. These are being pursued through advances in the basic sciences alongside energetic translational clinical research efforts.

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Health Sciences Medicine and Dentistry Perinatology, Pediatrics and Child Health
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