Article ID Journal Published Year Pages File Type
4176298 Seminars in Pediatric Infectious Diseases 2006 5 Pages PDF
Abstract

Vaccination against rotavirus disease has been a global preventive health priority since rotaviruses were first discovered in the 1970s. The first licensed rotavirus vaccine, RRV-TV, was removed from the market shortly after licensure because of an unexpected serious adverse event, intussusception. A pentavalent rotavirus vaccine, PRV, is the second FDA-licensed rotavirus vaccine and does not signal the risk observed with RRV-TV. The properties and large safety study results of PRV are reviewed here.

Related Topics
Health Sciences Medicine and Dentistry Perinatology, Pediatrics and Child Health
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