Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4176298 | Seminars in Pediatric Infectious Diseases | 2006 | 5 Pages |
Abstract
Vaccination against rotavirus disease has been a global preventive health priority since rotaviruses were first discovered in the 1970s. The first licensed rotavirus vaccine, RRV-TV, was removed from the market shortly after licensure because of an unexpected serious adverse event, intussusception. A pentavalent rotavirus vaccine, PRV, is the second FDA-licensed rotavirus vaccine and does not signal the risk observed with RRV-TV. The properties and large safety study results of PRV are reviewed here.
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Authors
David O. Matson,