| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4180226 | Biological Psychiatry | 2008 | 9 Pages |
Abstract
The replication of association of AKT1 gene variants in a further Caucasian family sample adds support for involvement of AKT signaling in schizophrenia, perhaps encompassing a broader clinical phenotype that includes mood dysregulation. We show that AKT signaling might be compromised in schizophrenic and bipolar patients via reduced RNA expression of specific AKT isoforms.
Related Topics
Life Sciences
Neuroscience
Biological Psychiatry
Authors
Dawn L. Thiselton, Vladimir I. Vladimirov, Po-Hsiu Kuo, Joseph McClay, Brandon Wormley, Ayman Fanous, Francis A. O'Neill, Dermot Walsh, Edwin J.C.G. Van den Oord, Kenneth S. Kendler, Brien P. Riley,