| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4186646 | Journal of Affective Disorders | 2010 | 7 Pages |
Abstract
Neuroticism was associated with stable neural activity in regions implicated in emotional processing and regulation for women but not men. Among women, Neuroticism prospectively predicted depressive symptoms through greater activity in the right hippocampus, suggesting one neural mechanism between Neuroticism and depression for women. Identifying responsible mechanisms for the association between Neuroticism and psychiatric disorders may help guide research on pharmacological interventions for such disorders across the lifespan.
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Authors
Angelina R. Sutin, Lori L. Beason-Held, Vonetta M. Dotson, Susan M. Resnick, Paul T. Jr.,