Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4188610 | Psiquiatría Biológica | 2015 | 7 Pages |
Abstract
The sub-chronic scheme of NMDA antagonists represents the most reliable model for the study of cognitive changes associated with schizophrenia. Cognitive impairment, as well as a pro-cognitive effect mediated by NMDA and 5-HT6, may be explained by a joint regulation of these receptors to modulate the release of distinct neurotransmitters, such as glutamate. This represents a complex interaction that requires ongoing research to clarify the mechanisms at play.
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Authors
Alfredo Briones Aranda, José Eduardo Suárez Santiago, Manuela Castellanos Pérez, VÃctor Manuel Vega Villa,