Article ID Journal Published Year Pages File Type
4195666 Biomedical and Environmental Sciences 2016 10 Pages PDF
Abstract
Our results indicated that p21 was responsible for the downregulation of G2/M transition regulatory proteins and the bypass of mitosis induced by irradiation. Downregulation of p21 by siRNA resulted in G2-arrested cells entering into mitosis with serious DNA damage. This is the first report on elucidating the role of p21 in the bypass of mitosis.
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Health Sciences Medicine and Dentistry Public Health and Health Policy
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p21 is Responsible for Ionizing Radiation-induced Bypass of Mitosis
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