| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4195771 | Biomedical and Environmental Sciences | 2016 | 4 Pages |
Abstract
Brucellosis is one of the most widespread zoonotic diseases, with the most frequent complication being osteoarticular changes. The aim of this study was to assess the changes of C-terminal telopeptide of type II collagen (CTX-II) in patients infected with brucellosis. A total of 84 brucellosis patients and 43 volunteers were selected and divided into brucellosis vs. control groups. Serum samples were subjected to serological tests for brucellosis, and CTX-II levels in all samples were measured simultaneously with ELISA. The results showed that serum CTX-II levels in human brucellosis were higher than those of healthy controls, without a statistically significant difference, but serum CTX-II levels in male patients were significantly higher than those of female patients (P<0.05). This finding could indicate the biological changes in the cartilage and bone in human brucellosis.
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Authors
Zhi Jun ZHAO, Qiang LI, Xin ZHOU, Li MA, Li Qing XU, Pei Zhen YANG, Xian Ya MENG, Hui Zhen YU, Xiao Qing XU, Jian Ying CAO,