Integrated treatment for lower-limb stage II thromboangiitis obliterans by interventional therapy and oral administration of Chinese medicine: a randomized controlled clinical trial

ObjectiveTo observe if integrated treatment is better than other therapies for lower-limb stage II thromboangiitis obliterans (TAO).MethodsNinety lower-limb stage II or worse TAO patients were randomly divided into three groups: group A (30 cases) treated by intervention and oral administration of Chinese medicine; group B (30 cases) treated by intervention alone; and group C (30 cases) treated only with oral administration of Chinese medicine. Therapeutic effects were observed, including the cure rate; the recurrence rate after one month, three months, six months, nine months, and one year; the ankle brachial indexes; the incidence of complications; and the level of C-reactive protein and erythrocyte sedimentation rate.ResultsGroup A had significantly better clinically curative effects, related indexes, and outcomes during the long-term follow-up survey, than that of groups B and C.ConclusionIntegrated treatment is more effective for treating lower-limb stage II or worse TAO.