Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

ObjectiveTo probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome (PMS) and reveal partial microcosmic mechanisms of adverse flow of liver-qi.MethodsEstradiol (E2) and progesterone (P) levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.ResultsIn the group of PMS with adverse flow of liver-qi, the secretive peak value of E2 and P at the follicular phase significantly decreased, and the secretive peak value at the luteal phase did not come into being.ConclusionsLow E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi. One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2 and P.