Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4207692 | Clinics in Chest Medicine | 2008 | 9 Pages |
Abstract
Like the systemic inflammatory response syndrome (SIRS), the compensatory anti-inflammatory response syndrome (CARS) is a complex pattern of immunologic responses to severe infection or injury. The difference is that while SIRS is a proinflammatory response tasked with killing infectious organisms through activation of the immune system, CARS is a global deactivation of the immune system tasked with restoring homeostasis. Much research now suggests that the timing and relative magnitude of this response have a profound impact on patient outcomes.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Pulmonary and Respiratory Medicine
Authors
Nicholas S. Ward, Brian Casserly, Alfred Ayala,