| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4212974 | Respiratory Medicine CME | 2011 | 8 Pages |
Abstract
ObjectiveTo review the topic of alpha-1 antitrypsin (AAT) deficiency.MethodNarrative literature review.ResultsMuch work has been carried out on this condition with many questions being answered but still further questions remain.Discussion and conclusionsAAT deficiency is an autosomal co-dominantly inherited disease which affects the lungs and liver predominantly. The clinical manifestations, prevalence, genetics, molecular pathophysiology, screening and treatment recommendations are summarised in this review.
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Authors
Emer Kelly, Catherine M. Greene, Tomas P. Carroll, Noel G. McElvaney, Shane J. O’Neill,