Advances in Radiotherapy for Tumors Involving the Mediastinum

Various malignancies either arise from or spread into the mediastinum. Radiotherapy in the area of the mediastinum is challenging because of the proximity to other critical organs, such as the heart, lungs, esophagus, and spinal cord. With recent advances in imaging, treatment, and the understanding of tumor biology, these diseases now can be treated more effectively and safely. This article reviews such innovations in radiotherapy and discusses their applications in tumors that involve the mediastinum.