Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4218763 | Academic Radiology | 2011 | 8 Pages |
Abstract
Doxorubicin loaded microbubbles triggered with ultrasound provided enhanced, sustained drug delivery to tumors, reduced plasma and myocardium doxorubicin levels, and arresting tumor growth. The results suggest that in situ generation of nano particles provides a superior treatment over injection of free drug and also de novo synthesized nanoparticles.
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Authors
Michael C. BS, John R. PhD, Michael C. MD, Susan M. RDMS, Richard O. BS, Sarah B. MD, Emma E. MD, Margaret A. PhD,