High-resolution Diffusion-weighted Magnetic Resonance Imaging in Patients with Locally Advanced Breast Cancer

Differences in ADC distribution parameters and qualitative image features suggest that the sequences differ in their ability to capture tumor heterogeneity. These differences are not apparent when the mean is used to evaluate tumor ADC. In particular, differences found in lower ADC values are compatible with reduced partial voluming in rFOV DW MRI, suggesting that rFOV DW MRI may be valuable in imaging the lower ADCs expected to correspond to viable tumor in most invasive breast cancers.