A New Semi-quantitative Approach for Analysing 3T Diffusion Tensor Imaging of Optic Fibres and Its Clinical Evaluation in Glaucoma

The new approach seems to be robust and is clearly faster compared to the more tedious manual segmentation. Using diffusion tensor imaging at 3 T, it could be shown that there was increasing atrophy of the optical radiation (fourth neuron) with increasing age in patients with glaucoma. Compared to age-matched, healthy patients, more pronounced atrophy of the fourth neuron was found in patients with glaucoma.