Quantitative Assessment of Blood Volume and Permeability in Cerebral Mass Lesions using Dynamic Contrast-Enhanced Computed Tomography in the Dog

Low-grade gliomas do not consistently demonstrate elevated vascular parameters, whereas Grade III gliomas and non-neoplastic intra-axial lesions have elevated PS. Ratios between such lesions and normal brain may prove useful for differentiating types of lesions. These findings resemble those previously reported in similar lesions in people indicating that the dog may act as a good model for intracranial masses for the study of lesion angiogenesis and response to therapy.