Efficacy of single voxel 1H MR spectroscopic imaging at 3 T for the differentiation of benign and malign breast lesions

PurposeThe aim of our study was to evaluate the effect of 1H Magnetic Resonance Spectroscopy (MRS) in differentiating breast lesions.Materials and methodsSingle voxel 1H Magnetic Resonance Spectroscopy (1H-MRS) was performed with 3 T magnet in 45 women. The choline cut off point was set semi-quantitavely. Sensitivity, specificity and accuracy of MRS were calculated.ResultsTwenty-four of 25 (96%) malignant and 9 of 26 (35%) benign lesions had choline peak. With the use cutoff value of 19,5 MRS provided a 96% sensitivity, 65% specificity and 80% accuracy.ConclusionMRS has a high diagnostic accuracy in differentiating breast lesions.