Comparison of field-of-view (FOV) optimized and constrained undistorted single shot (FOCUS) with conventional DWI for the evaluation of prostate cancer

ObjectivesQualitative and quantitative comparison of the application value of diffusion-weighted imaging (DWI) magnetic resonance imaging based on field-of-view (FOV) optimized and constrained undistorted single shot (FOCUS) with the standard single-shot echo-planar imaging (ss-EPI) in patients with prostate cancer.MethodsA total of 28 patients with 33 prostate cancers underwent ss-EPI and FOCUS DWI. Two independent readers assessed image studies.ResultsImage qualities of FOCUS were rated superior to ss-EPI (P< .001). The mean apparent diffusion coefficient value of 33 cancers was 974.030×10− 6 mm2/s and 941.727×10− 6 mm2/s, respectively, and the difference was statistically significant (t= 2.579, P= .015).ConclusionsFOCUS as a high-resolution DWI technique has potential clinical utility.