Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4221577 | Clinical Imaging | 2012 | 6 Pages |
Abstract
PurposeThis study aimed to evaluate iron levels in cardiac and hepatic tissues using magnetic resonance imaging (MRI) T2⁎.MethodsCardiac and hepatic MRI was performed for 93 patients with β-thalassemia major.ResultsCardiac T2⁎ was in the range of 2.9–56.6 ms. Myocardial siderosis was detected in 44% of patients; 25 patients had moderate and severe siderosis with serum ferritin level (SFL) of 576–10,284 ng/ml. There was a significant correlation between SFL and cardiac T2⁎ (p<.001).ConclusionsThe effective role of MRI as a noninvasive producible method in measurement of iron concentration in tissues is not accessible with conventional techniques.
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Authors
Bibi Shahin Shamsian, Shadi Abdar Esfahani, Hani Milani, Shahram Akhlaghpoor, Saeid Mojtahedzadeh, Abdollah Karimi, Ahmad Reza Shamshiri, Samin Alavi, Alieh Safari, Nima Rezaei, Mohammad Taghi Arzanian,