| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4224839 | European Journal of Radiology | 2016 | 7 Pages |
PurposeTo investigate if 18F-FDG PET/MRI can improve the diagnostic performance of TNM staging and help make an accurate decision for resectability in patients with gastric cancer compared to MDCT.Materials and methodsForty-two patients with histologically confirmed gastric cancers underwent preoperative MDCT and 18F-FDG PET/MRI. M-staging and resectability was assessed in all patients, and T- and N-staging was evaluated in 30 of 42 patients who underwent curative gastrectomy. Two abdominal radiologists independently assessed their MDCT images and 18F-FDG PET/MRI and determined preoperative TNM staging and resectability of gastric cancers. Diagnostic performance with MDCT and 18F-FDG PET/MRI were compared using McNemar’s test and receiver operating characteristic analysis.ResultsDiagnostic accuracies for T and N staging were not significantly different between MDCT and 18F-FDG PET/MRI in both readers. However, 18F-FDG PET/MRI showed significantly improved diagnostic accuracy for M staging in one reader (P = 0.008) and marginal improvement in the other reader (P = 0.063) compared to MDCT. Regarding the resectability of gastric cancers, diagnostic accuracy (92.9% for both readers) of 18F-FDG PET/MRI was significantly higher than that (76.2% for reader 1 and 64.3% for reader 2) of MDCT in both readers (P < 0.05).Conclusion18F-FDG PET/MRI may improve diagnostic accuracy for preoperative M staging as well as resectability of gastric cancers compared to MDCT.
