Article ID Journal Published Year Pages File Type
4224858 European Journal of Radiology 2015 7 Pages PDF
Abstract

•Multimodal functional CT comprising of NCCT, PCT and CTA, provides a one-stop-shop for rapid stroke imaging.•PCT can differentiate infarcted tissue from penumbra. PCT can also assess the collateral circulation and prediction hemorrhagic transformation or malignant edema.•CTA evaluates the vasculature and can help identify candidates for endovascular treatment.•Utilization of functional CT for therapy selection or extension of treatment time-window has not yet been confirmed in clinical trials. The EXTEND phase 3 trial is one of the ongoing studies.

Advanced imaging techniques have extended beyond traditional anatomic imaging and progressed to dynamic, physiologic and functional imaging. Neuroimaging is no longer a mere diagnostic tool. Multimodal functional CT, comprising of NCCT, PCT and CTA, provides a one-stop-shop for rapid stroke imaging. Integrating those imaging findings with pertinent clinical information can help guide subsequent treatment decisions, medical management and follow-up imaging selection. This review article will briefly discuss the indication and utility of each modality in acute stroke imaging.

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