Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4237127 | Journal of Vascular and Interventional Radiology | 2016 | 12 Pages |
Abstract
Oxygen-ozone therapy breaks down proteoglycan GAGs that maintain disc osmotic pressure, dehydrating the nucleus pulposus and reducing intervertebral disc volume. This is likely a primary mechanism by which ozone relieves nerve root compression and alleviates herniated disc-related pain. Additionally, 2 wt% ozone appears to interact with intradiscal cytokines, generating an antiinflammatory response that may contribute to symptom improvement.
Keywords
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Authors
Kieran MB, BCh, FRCPC, FSIR, Gavin BA, Jim PhD, Chett PhD, MBA, Kuberan PhD, Xylophone PhD, Thomas BS, Mario MD,