Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4237852 | Journal of Vascular and Interventional Radiology | 2013 | 8 Pages |
Abstract
A sophisticated understanding of the rapidly changing field of oncology, including a broad knowledge of oncologic disease and the therapies available to treat them, is fundamental to the interventional radiologist providing oncologic therapies, and is necessary to affirm interventional oncology as one of the four pillars of cancer care alongside medical, surgical, and radiation oncology. The first part of this review intends to provide a concise overview of the fundamentals of oncologic clinical trials, including trial design, methods to assess therapeutic response, common statistical analyses, and the levels of evidence provided by clinical trials.
Keywords
FDAORRmRECISTTTPEASLDCRNCCNHCCPFsEuropean Association for the Study of the Liverprogression-free survivalstable diseaseRECISTTime to progressionWorld Health OrganizationFood and Drug AdministrationNational Comprehensive Cancer NetworkResponse Evaluation Criteria in Solid Tumorsmodified Response Evaluation Criteria in Solid Tumorsoverall response rateDisease control ratePartial responsecomplete responseHepatocellular carcinomaWHO
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Authors
Ryan MD, Michael MD, Daniel Y. MD, Elias MD, Jeremy MD, Todd MD, Khairuddin MD, Robert K. MD, Kent MD, Richard DO, Ramona MD, Scott MD, James MD, Howard B. MD, Albert A. MD, Robert L. MD, Robert J. MD, Riad MD, MBA,