Detection of Extracellular Genomic DNA Scaffold in Human Thrombus: Implications for the Use of Deoxyribonuclease Enzymes in Thrombolysis

Article ID	Journal	Published Year	Pages	File Type
4238997	Journal of Vascular and Interventional Radiology	2012	7 Pages	PDF

Abstract

Extensive detection of genomic DNA associated with histones in the extracellular matrix of human and mouse thrombi suggest the presence of a new thrombus-associated scaffold.

Keywords

tPA DAPI TLR LDI H-E 4′,6-diamidino-2-phenylindole MPO Laser Doppler imaging neutrophil extracellular trap Toll-like receptor NET tissue plasminogen activator myeloperoxidase Hematoxylin and Eosin

Related Topics

Health Sciences Medicine and Dentistry Radiology and Imaging

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Detection of Extracellular Genomic DNA Scaffold in Human Thrombus: Implications for the Use of Deoxyribonuclease Enzymes in Thrombolysis

Authors

Rahmi MD, PhD, Hassan MD, Michael T. MD, Marc MD, PhD, Martin MD, PhD, Stephan MD,