| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4241443 | Journal of Vascular and Interventional Radiology | 2008 | 9 Pages |
Abstract
ADAMTS-1 was significantly upregulated in thrombosed hemodialysis grafts by mass spectrometric analysis and Western blot analysis. Expression was localized to adventitial macrophages and leukocytes. It is hypothesized that ADAMTS-1 may be related to intimal hyperplasia in hemodialysis vascular access grafts. Future work is planned on inhibiting ADAMTS-1 expression and determining the effect on intimal hyperplasia in hemodialysis grafts.
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Authors
Sanjay MD, Nathan PhD, Alex A. PhD, Sreekumar PhD, Jaywant PhD, Haraldur MD, Michael A. MD, Luisa PhD, Debabrata PhD,