Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4248467 | Radiology Case Reports | 2007 | 5 Pages |
Abstract
Granulocyte colony–stimulating factor (GCSF), often used as an adjunct to chemotherapy, can pose a dilemma in differentiating the associated bone marrow changes from metastatic disease on magnetic resonance imaging. The phenomenon has been previously reported in children undergoing treatment for primary musculoskeletal malignancies [1 and 2]. We present a case of GCSF-induced marrow reconversion simulating neuroblastoma metastases on MR imaging. An interesting observation in our case was intense abnormal signal in a pattern of metaphyseal bands, which, to our knowledge, was not previously reported in the English literature to be associated with GCSF-induced marrow reconversion.
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Authors
Jason C. Naples, Mihra S. Taljanovic, Michael L. Graham, Tim B. Hunter,