Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4256952 | Transplantation Proceedings | 2013 | 4 Pages |
Abstract
Recurrent or “de novo” AA amyloidosis in the renal allograft is rarely described. We describe a case of severe nephrotic syndrome in a recipient of a kidney graft with a previous diagnosis of polycystic nephropathy caused by AA amyloidosis diagnosed only after the renal transplantation. The disease was possibly a tumor necrosis factor receptor–associated periodic syndrome (TRAPS). TRAPS is a rare hereditary inflammatory disease never reported to the best of our knowledge, as a de novo diagnosis in the transplantation setting. Biopsy of the renal graft, indicated for the onset of heavy proteinuria, and genetic investigation provided the clues for diagnosis.
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Authors
M. Messina, G. Daidola, G. Restagno, A. Lavacca, A. Ranghino, L. Biancone, G.P. Segoloni,