Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4259929 | Transplantation Proceedings | 2012 | 4 Pages |
Abstract
Currently, there are two major options for the successful and timely transplantation of sensitized kidney transplant recipients: (1) avoidance of the sensitization barrier using special allocation programs, or (2) desensitization. In the case of broadly sensitized kidney patients, a combination of both options might be necessary. This review focuses on new advances in desensitization of crossmatch-positive kidney transplant recipients which include immunoadsorption and the administration of new substances such as the complement C5 inhibitor eculizumab. Finally, integrated algorithms that combine different measures are acknowledged.
Related Topics
Health Sciences
Medicine and Dentistry
Surgery
Authors
C. Morath, G. Opelz, M. Zeier, C. Süsal,