Influence of Perioperational Acid-Base Balance Disorders on Early Graft Function in Kidney Transplantation

At the beginning of reperfusion there is increasing metabolic acidosis with simultaneous expiratory pCO2 as compensation. A greater relative increase in expiratory air pCO2 was correlated with a higher incidence of early graft loss. The higher intensity of metabolic acidosis correlated with worse renal function at 6 months after transplantation. Elderly donor age and fewer HLA-matched antigens correlated with greater intensity of metabolic acidosis during 30 minutes of kidney reperfusion.