When should radiotherapy be used after radical prostatectomy? The RADICALS-RT Trial

Despite two recent trials of the role of early radiotherapy following radical prostatectomy, there remains no consensus as to best practice and clinicians tend to base their decisions around MDT discussion and pathological risk factors. This paper develops the argument for international Intergroup trial, RADICALS-RT, which is now recruiting, and which is our opportunity to resolve this important issue.