| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4269790 | The Journal of Sexual Medicine | 2014 | 10 Pages |
Abstract
HDACâinduced pathological signaling in response to BCNI contributes to penile vascular dysfunction. Pharmacological inhibition of HDAC prevents penile fibrosis, normalizes fibronectin expression, and preserves erectile function. The HDAC pathway may represent a suitable target in preventing the progression of ED occurring postâradical prostatectomy. Hannan JL, Kutlu O, Stopak BL, Liu X, Castiglione F, Hedlund P, Burnett AL, and Bivalacqua TJ. Valproic acid prevents penile fibrosis and erectile dysfunction in cavernous nerveâinjured rats. J Sex Med 2014;11:1442-1451.
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Authors
Johanna L. PhD, Omer MD, Bernard L. BS, Xiaopu BS, Fabio MD, Petter PhD, Arthur L. MD, MBA, Trinity J. MD, PhD,