Role for Tyrosine Kinases in Contraction of Rat Penile Small Arteries

This study suggests that activation of tyrosine kinases is involved in contraction of rat penile smooth muscle probably by regulation of calcium entry through l-type calcium channels. These findings may have implications for the selections of novel add on anticancer treatments, e.g., inhibitors of tyrosine kinases, and for novel approaches to treat erectile dysfunction. Villalba N, Kun A, Stankevicius E, and Simonsen U. Role for tyrosine kinases in contraction of rat penile small arteries.