ORIGINAL RESEARCH-WOMEN'S SEXUAL HEALTH: Successful Transcutaneous Electrical Nerve Stimulation in Two Women with Restless Genital Syndrome: The Role of Aδ- and C-Nerve Fibers

Conventional TENS treatment is a promising therapy for ReGS, but further controlled research is warranted. Preorgasmic and orgasmic genital sensations in ReGS are transmitted by Aδ and C fibers and are inhibited by Aβ fibers. A neurological hypothesis on the pathophysiology of ReGS encompassing its clinical symptomatology, TENS, and drug treatment is put forward. Waldinger MD, Lint GJ, Venema PL, van Gils AP, and Schweitzer DH. Successful transcutaneous electrical nerve stimulation in two women with restless genital syndrome: The role of Aδ- and C-nerve fibers.