Derangements in Endothelial Cell-to-Cell Junctions Involved in the Pathogenesis of Hypercholesterolemia-Induced Erectile Dysfunction

Down-regulation of the endothelial cell-to-cell junctions and decreased endothelial content in the corpus cavernosum might play a major role in the deterioration of erectile function in hypercholesterolemic mice. Ryu J-K, Zhang LW, Jin H-R, Piao S, Choi MJ, Tuvshintur B, Tumurbaatar M, Shin SH, Han J-Y, Kim WJ, and Suh J-K. Derangements in endothelial cell-to-cell junctions involved in the pathogenesis of hypercholesterolemia-induced erectile dysfunction. J Sex Med 2009;6:1893-1907.