Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4272044 | The Journal of Sexual Medicine | 2010 | 10 Pages |
Abstract
In diabetic rats, prolonged therapy with imatinib improves diabetes-related ED and vascular function, which may involve normalization of high glucose levels and restoration of PTK activation. Future studies are needed to elaborate on the actions of imatinib on diabetic vascular complications. Gur S, Kadowitz PJ, and Hellstrom WJG. A protein tyrosine kinase inhibitor, imatinib mesylate (Gleevec), improves erectile and vascular function secondary to a reduction of hyperglycemia in diabetic rats.
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Authors
Serap PhD, Philip J. PhD, Wayne J.G. MD, FACS,